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Serological biomarker models composed of luteinizing hormone, kisspeptin, vitamin D and estradiol, and their clinical test value in girls

Objective: Central precocious puberty (CPP) may lead to premature pubertal onset. While the GnRH stimulation test remains the gold standard, its invasive nature and prolonged procedure limit clinical utility, particularly in pediatric populations. Emerging biomarkers, including luteinizing hormone,...

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Principais autores: Mingyu Shao, Zhiyi Jia, Tongtong Liu, Xiaopeng Zhang
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2026-01-01
Series:Jornal de Pediatria
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Acceso en liña:http://www.sciencedirect.com/science/article/pii/S0021755725001652
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