IL-17RA-Signaling Modulates CD8+ T Cell Survival and Exhaustion During Trypanosoma cruzi Infection

The IL-17 family contributes to host defense against many intracellular pathogens by mechanisms that are not fully understood. CD8+ T lymphocytes are key elements against intracellular microbes, and their survival and ability to mount cytotoxic responses are orchestrated by several cytokines. Here,...

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Autors principals:	Jimena Tosello Boari, Cintia L. Araujo Furlan, Facundo Fiocca Vernengo, Constanza Rodriguez, María C. Ramello, María C. Amezcua Vesely, Melisa Gorosito Serrán, Nicolás G. Nuñez, Wilfrid Richer, Eliane Piaggio, Carolina L. Montes, Adriana Gruppi, Eva V. Acosta Rodríguez
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2018-10-01
Col·lecció:	Frontiers in Immunology
Matèries:	IL-17 chagas disease immunity cellular CD8+ T cells exhausted T cells
Accés en línia:	https://www.frontiersin.org/article/10.3389/fimmu.2018.02347/full
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