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Exploring the Biological Potency of Carotenoids Against Alzheimer’s Disease: An Integrated Approach of Molecular Docking and Molecular Dynamics

Alzheimer’s disease (AD) is a multifactorial neurodegenerative disorder characterized by cholinergic dysfunction, amyloid-β aggregation, mitochondrial stress, and aberrant kinase activity. Carotenoids, naturally occurring pigments with antioxidant and neuroprotective properties, have emerged as prom...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Meriem Khedraoui, El Mehdi Karim, Imane Yamari, Abdelkbir Errougui, Doni Dermawan, Nasser Alotaiq, Samir Chtita
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2026-04-01
Schriftenreihe:Current Issues in Molecular Biology
Schlagworte:
Alzheimer’s disease
carotenoids
Hopkinsiaxanthin
molecular docking
molecular dynamics
MM/PBSA
Online-Zugang:https://www.mdpi.com/1467-3045/48/4/407
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