DDX60 protects ischemic myocardial injury and heart dysfunction by improving mitochondrial function via promoting Arl2 mRNA translation

Abstract Mitochondrial dysfunction is increasingly recognized as a pivotal driver of cardiomyocyte apoptosis and cardiac deterioration following myocardial infarction (MI). This study identifies a significant upregulation of DDX60 in cardiomyocytes under hypoxic conditions. Elevated DDX60 levels enh...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Tianyou Yuan, Changzuan Zhou, Yifan Long, Xiaoqiang Chen, Longzhe Gao, Ya Li, Songwen Chen, Xiaofeng Lu, Juan Xu, Xiaoyu Wu, Genqing Zhou, Shaowen Liu, Wenyi Yang, Yong Wei, Lidong Cai
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Springer 2025-09-01
Serie:	Cellular and Molecular Life Sciences
Soggetti:	Cardiomyocyte apoptosis Mitochondrial function Myocardial infarction DDX60 Arl2
Accesso online:	https://doi.org/10.1007/s00018-025-05839-x
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!