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Cancer-Specific Delivery of Proteolysis-Targeting Chimeras (PROTACs) and Their Application to Cancer Immunotherapy

Proteolysis-targeting chimeras (PROTACs) are rapidly emerging as a potential therapeutic strategy for cancer therapy by inducing the degradation of tumor-overexpressing oncogenic proteins. They can specifically catalyze the degradation of target oncogenic proteins by recruiting E3 ligases and utiliz...

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Autores principales: Yujeong Moon, Seong Ik Jeon, Man Kyu Shim, Kwangmeyung Kim
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI AG 2023-01-01
Colección:Pharmaceutics
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Acceso en línea:https://www.mdpi.com/1999-4923/15/2/411
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