In-silico evaluation of novel quercetin derivatives targeting Plasmodium falciparum dihydrofolate reductase for antimalarial activity

Abstract The global rise in malaria mortality is significantly influenced by the increasing resistance of Plasmodium falciparum to widely used and affordable antimalarial drugs, among other contributing factors, emphasizing the need for novel therapeutic agents. In this study, a series of 84 quercet...

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Detalhes bibliográficos

Principais autores:	Mansita Saha, Krishna Jyoti Deka, Sabnam Nargis, Dhrubajyoti Gogoi, Pallab Kumar Nath, Debarupa Dutta Chakraborty, Prithviraj Chakraborty
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Springer 2026-06-01
coleção:	Discover Chemistry
Assuntos:	Malaria Ligands DHFR-TS Molecular docking Molecular dynamics ADMET
Acesso em linha:	https://doi.org/10.1007/s44371-026-00799-y
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