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In-silico evaluation of novel quercetin derivatives targeting Plasmodium falciparum dihydrofolate reductase for antimalarial activity

Abstract The global rise in malaria mortality is significantly influenced by the increasing resistance of Plasmodium falciparum to widely used and affordable antimalarial drugs, among other contributing factors, emphasizing the need for novel therapeutic agents. In this study, a series of 84 quercet...

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Huvudupphov: Mansita Saha, Krishna Jyoti Deka, Sabnam Nargis, Dhrubajyoti Gogoi, Pallab Kumar Nath, Debarupa Dutta Chakraborty, Prithviraj Chakraborty
Materialtyp: Artigo
Språk:Inglês
Utgiven: Springer 2026-06-01
Serie:Discover Chemistry
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Länkar:https://doi.org/10.1007/s44371-026-00799-y
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