Doxycycline inhibits MMPs via modulation of plasminogen activators in focal cerebral ischemia
Tetracyclines inhibit matrix metalloproteinases (MMPs) and reduce infarction volume following cerebral ischemia. In this thesis an involvement of urokinase could be proven. Cerebral ischemia in rats was induced for 3 h followed by 24 h reperfusion (suture model). Each 6 animals received orally eithe...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2007-03-01
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| Serie: | Neurobiology of Disease |
| Soggetti: | |
| Accesso online: | http://www.sciencedirect.com/science/article/pii/S0969996106002853 |
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