Macrophage targeted polymeric curcumin nanoparticles limit intracellular survival of Mycobacterium tuberculosis through induction of autophagy and augment anti-TB activity of isoniazid in RAW 264.7 macrophages

Rapid emergence of antibiotic resistance in tuberculosis has left us with limited resources to treat and manage multi drug resistant (MDR) cases of tuberculosis, prompting the development of novel therapeutics. Mycobacterium tuberculosis (MTB) perturbs the host protective pathways for its survival,...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Pramod Kumar Gupta, Priyanka Jahagirdar, Devavrat Tripathi, Padma V. Devarajan, Savita Kulkarni
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2023-07-01
Colecção:	Frontiers in Immunology
Assuntos:	mycobacterium tuberculosis autophagy host-directed therapeutics curcumin multi drug resistance phagosome lysosome fusion
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1233630/full
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!