Macrophage targeted polymeric curcumin nanoparticles limit intracellular survival of Mycobacterium tuberculosis through induction of autophagy and augment anti-TB activity of isoniazid in RAW 264.7 macrophages

Rapid emergence of antibiotic resistance in tuberculosis has left us with limited resources to treat and manage multi drug resistant (MDR) cases of tuberculosis, prompting the development of novel therapeutics. Mycobacterium tuberculosis (MTB) perturbs the host protective pathways for its survival,...

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Egile Nagusiak:	Pramod Kumar Gupta, Priyanka Jahagirdar, Devavrat Tripathi, Padma V. Devarajan, Savita Kulkarni
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Frontiers Media S.A. 2023-07-01
Saila:	Frontiers in Immunology
Gaiak:	mycobacterium tuberculosis autophagy host-directed therapeutics curcumin multi drug resistance phagosome lysosome fusion
Sarrera elektronikoa:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1233630/full
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