Identification of Vinyl Sulfone Derivatives as EGFR Tyrosine Kinase Inhibitor: In Vitro and In Silico Studies

Epidermal growth factor receptor (EGFR), overexpressed in many types of cancer, has been proved as a high potential target for targeted cancer therapy due to its role in regulating proliferation and survival of cancer cells. In the present study, a series of designed vinyl sulfone derivatives was sc...

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Principais autores:	Thitinan Aiebchun, Panupong Mahalapbutr, Atima Auepattanapong, Onnicha Khaikate, Supaphorn Seetaha, Lueacha Tabtimmai, Chutima Kuhakarn, Kiattawee Choowongkomon, Thanyada Rungrotmongkol
格式:	Artigo
語言:	Inglês
出版:	MDPI AG 2021-04-01
叢編:	Molecules
主題:	EGFR tyrosine kinase vinyl sulfone derivatives in silico study kinase assay cytotoxicity assay
在線閱讀:	https://www.mdpi.com/1420-3049/26/8/2211
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