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Identification of Vinyl Sulfone Derivatives as EGFR Tyrosine Kinase Inhibitor: In Vitro and In Silico Studies

Epidermal growth factor receptor (EGFR), overexpressed in many types of cancer, has been proved as a high potential target for targeted cancer therapy due to its role in regulating proliferation and survival of cancer cells. In the present study, a series of designed vinyl sulfone derivatives was sc...

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Principais autores: Thitinan Aiebchun, Panupong Mahalapbutr, Atima Auepattanapong, Onnicha Khaikate, Supaphorn Seetaha, Lueacha Tabtimmai, Chutima Kuhakarn, Kiattawee Choowongkomon, Thanyada Rungrotmongkol
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2021-04-01
Colecção:Molecules
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Acesso em linha:https://www.mdpi.com/1420-3049/26/8/2211
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