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Dysbetalipoproteinaemia in genetically predisposed Ghanaians

Abstract Background Dysbetalipoproteinaemia (dysβ) is a genetic lipid disorder characterised by accumulated remnant lipoproteins, leading to mixed hyperlipidaemia and increased cardiovascular risk. It is primarily associated with apolipoprotein E (apoE) ε2/ε2 homozygosity, although variants, such as...

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Principais autores: Richmond Owusu Ateko, Adrian David Marais, Dirk Jacobus Blom, Samuel Mawuli Adadey, Nicholas Ekow Thomford, Diane Mary Blackhurst
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-11-01
Serier:Lipids in Health and Disease
Fag:
Dysbetalipoproteinaemia
Apolipoprotein e
Polyacrylamide gradient gel electrophoresis
Cardiovascular disease
Remnant lipoproteins
PCR-RFLP
Online adgang:https://doi.org/10.1186/s12944-025-02787-0
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