Drug-drug interaction between dolutegravir and artemether-lumefantrine in HIV and malaria mono- and co-infections: a pharmacogenetic analysis from Ghana

Abstract Background Human Immunodeficiency Virus and malaria are significant public health challenges in sub-Saharan Africa, contributing substantially to morbidity and mortality in the region. The trajectory of HIV and malaria mono- and coinfections may be different with presentations of drug-drug...

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Autores principales:	Nicholas Ekow Thomford, Tracy Kellermann, Joel Adu Twum, John Anyimadu, Charné Dixon, Dennis Sappor, Dee Blackhurst, Prince Amoah Barnie, Oksana Ryabinina, Samuel Badu Nyarko, Robert Peter Biney, Martins Ekor, George B. Kyei
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2025-08-01
Colección:	AIDS Research and Therapy
Materias:	CYP3A4 CYP3A5 UGT1A1 HIV DTG Viral load
Acceso en línea:	https://doi.org/10.1186/s12981-025-00787-9
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