Transcriptional dysregulation in NIPBL and cohesin mutant human cells.

Cohesin regulates sister chromatid cohesion during the mitotic cell cycle with Nipped-B-Like (NIPBL) facilitating its loading and unloading. In addition to this canonical role, cohesin has also been demonstrated to play a critical role in regulation of gene expression in nondividing cells. Heterozyg...

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Principais autores:	Jinglan Liu, Zhe Zhang, Masashige Bando, Takehiko Itoh, Matthew A Deardorff, Dinah Clark, Maninder Kaur, Stephany Tandy, Tatsuro Kondoh, Eric Rappaport, Nancy B Spinner, Hugo Vega, Laird G Jackson, Katsuhiko Shirahige, Ian D Krantz
Format:	Artigo
Jezik:	Inglês
Izdano:	Public Library of Science (PLoS) 2009-05-01
Serija:	PLoS Biology
Online dostop:	http://europepmc.org/articles/PMC2680332?pdf=render
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