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Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19

The immune response is key in determining disease severity of COVID19. Here Nouailles et al., apply bulk proteomics and scRNA-Seq of lung and blood samples of SARS-CoV-2 infected Syrian hamsters and provide a temporal atlas of the systemic and pulmonary cellular responses.

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Principais autores: Geraldine Nouailles, Emanuel Wyler, Peter Pennitz, Dylan Postmus, Daria Vladimirova, Julia Kazmierski, Fabian Pott, Kristina Dietert, Michael Muelleder, Vadim Farztdinov, Benedikt Obermayer, Sandra-Maria Wienhold, Sandro Andreotti, Thomas Hoefler, Birgit Sawitzki, Christian Drosten, Leif E. Sander, Norbert Suttorp, Markus Ralser, Dieter Beule, Achim D. Gruber, Christine Goffinet, Markus Landthaler, Jakob Trimpert, Martin Witzenrath
Formato: Artigo
Idioma:Inglês
Publicado: Nature Portfolio 2021-08-01
Series:Nature Communications
Acceso en liña:https://doi.org/10.1038/s41467-021-25030-7
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