Tricyclic Nucleobase Analogs and Their Ribosides as Substrates and Inhibitors of Purine-Nucleoside Phosphorylases III. Aminopurine Derivatives

Etheno-derivatives of 2-aminopurine, 2-aminopurine riboside, and 7-deazaadenosine (tubercidine) were prepared and purified using standard methods. 2-Aminopurine reacted with aqueous chloroacetaldehyde to give two products, both exhibiting substrate activity towards bacterial (<i>E. coli</i>) purine-...

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Autors principals:	Alicja Stachelska-Wierzchowska, Jacek Wierzchowski, Michał Górka, Agnieszka Bzowska, Ryszard Stolarski, Beata Wielgus-Kutrowska
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2020-02-01
Col·lecció:	Molecules
Matèries:	purine nucleoside phosphorylase nucleobase/nucleoside analogs chemo-enzymatic synthesis fluorescence nmr enzyme-substrate complexes
Accés en línia:	https://www.mdpi.com/1420-3049/25/3/681
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