Structural basis of tetanus toxin neutralization by native human monoclonal antibodies

Summary: Four potent native human monoclonal antibodies (mAbs) targeting distinct epitopes on tetanus toxin (TeNT) are isolated with neutralization potency ranging from approximately 17 mg to 6 mg each that are equivalent to 250 IU of human anti-TeNT immunoglobulin. TT0170 binds fragment B, and TT00...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Yueming Wang, Changwen Wu, Jinfang Yu, Shujian Lin, Tong Liu, Lipeng Zan, Nan Li, Po Hong, Xiaoli Wang, Zhenxing Jia, Jason Li, Yao Wang, Ming Zhang, Xiaohui Yuan, Chengming Li, Wenwen Xu, Weihong Zheng, Xinquan Wang, Hua-Xin Liao
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2021-05-01
Цуврал:	Cell Reports
Нөхцлүүд:	tetanus tetanus toxin toxin neutralization native human monoclonal antibody immunoglobulin ganglioside
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S2211124721004010
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!