Pancreatic α-cell sodium-glucose cotransporter 1 (SGLT1) does not appear to contribute to hyperglucagonemia and glucose intolerance in diabetic mice

Pancreatic α-cells secrete glucagon, a hormone that elevates blood glucose levels. In type 2 diabetes, high plasma glucagon levels are associated with hyperglycemia. However, the underlying mechanisms of increasing glucagon secretion remain unclear. We focused on the intrinsic regulatory mechanisms...

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Detalhes bibliográficos

Principais autores:	Yuichi Ikeuchi, Osamu Kikuchi, Masaki Kobayashi, Yoko Tabei, Hiromi Hashimoto, Ryosuke Kobayashi, Takuro Horii, Izuho Hatada, Takeshi Miyatsuka, Tadahiro Kitamura
Formato:	Artigo
Idioma:	Inglês
Publicado em:	The Japan Endocrine Society 2026-03-01
coleção:	Endocrine Journal
Assuntos:	glucagon pancreatic α-cell sodium–glucose cotransporter 1 type 2 diabetes
Acesso em linha:	https://www.jstage.jst.go.jp/article/endocrj/73/3/73_EJ25-0403/_html/-char/en
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