TRPM7 kinase regulates α-cell proliferation and glucagon production in mice

Objectives: Glucagon is essential for maintaining glucose homeostasis, yet the molecular mechanisms governing α-cell function remain incompletely understood. Transient receptor potential melastatin 7 (TRPM7) is a ubiquitously expressed ion channel with an intrinsic kinase domain, which regulates the...

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Bibliografiska uppgifter

Huvudupphov:	Severin Boulassel, Pascale C.F. Schreier, Andreas Beck, Hyeri Choi, Anna M. Melyshi, Peter S. Reinach, Megan Duraj, Mikhail Vinogradov, Bibiazhar Suleimen, Johanna Berger, Katharina Jacob, Andreas Breit, Susanna Zierler, Ingrid Boekhoff, Thomas Gudermann, Noushafarin Khajavi
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Elsevier 2026-02-01
Serie:	Molecular Metabolism
Ämnen:	TRPM7 Glucagon secretion α-cell identity α-cell proliferation mTOR signaling
Länkar:	http://www.sciencedirect.com/science/article/pii/S2212877826000013
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