Porphyromonas gingivalis outer membrane vesicles prevent the induction of tolerogenic dendritic cells by first trimester trophoblast cells

IntroductionPeriodontitis is a risk factor for adverse pregnancy outcomes, yet the mechanisms linking Porphyromonas gingivalis (Pg) to placental immune dysregulation remain unclear. Outer membrane vesicles (OMV) derived from this pathogen act as systemic virulence mediators, but their impact on mate...

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Bibliografische Detailangaben

Hauptverfasser:	Brenda Lara, Ana Schafir, Ailén Fretes, Lourdes Materazzi, Fátima Merech, Daiana Rios, Rosanna Ramhorst, Claudia Pérez Leirós, Daiana Vota, Soledad Gori, Vanesa Hauk
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2026-05-01
Schriftenreihe:	Frontiers in Immunology
Schlagworte:	immunomodulation P. gingivalis outer membrane vesicles periodontal disease tolerogenic dendritic cells trophoblast cells
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1814664/full
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