Porphyromonas gingivalis outer membrane vesicles prevent the induction of tolerogenic dendritic cells by first trimester trophoblast cells

IntroductionPeriodontitis is a risk factor for adverse pregnancy outcomes, yet the mechanisms linking Porphyromonas gingivalis (Pg) to placental immune dysregulation remain unclear. Outer membrane vesicles (OMV) derived from this pathogen act as systemic virulence mediators, but their impact on mate...

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Hlavní autoři:	Brenda Lara, Ana Schafir, Ailén Fretes, Lourdes Materazzi, Fátima Merech, Daiana Rios, Rosanna Ramhorst, Claudia Pérez Leirós, Daiana Vota, Soledad Gori, Vanesa Hauk
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2026-05-01
Edice:	Frontiers in Immunology
Témata:	immunomodulation P. gingivalis outer membrane vesicles periodontal disease tolerogenic dendritic cells trophoblast cells
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1814664/full
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