Anomalous Levels of CD47/Signal Regulatory Protein Alpha in the Hippocampus Lead to Excess Microglial Engulfment in Mouse Model of Perioperative Neurocognitive Disorders

BackgroundPerioperative neurocognitive disorders (PNDs) are common complications of surgical patients, which can lead to prolonged hospitalization, increased complications, and decreased independence and quality of life. However, the underlying molecular mechanisms of PND remain largely obscure. Mic...

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Autors principals:	Min Shui, Yi Sun, Dandan Lin, Ziyi Xue, Jianhui Liu, Anshi Wu, Changwei Wei
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2022-03-01
Col·lecció:	Frontiers in Neuroscience
Matèries:	CD47 SIRPα do not eat me microglia phagocytosis pruning
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fnins.2022.788675/full
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