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Preparation and Characterization of Cationic PLA-PEG Nanoparticles for Delivery of Plasmid DNA

<p>Abstract</p> <p>The purpose of the present work was to formulate and evaluate cationic poly(lactic acid)-poly(ethylene glycol) (PLA-PEG) nanoparticles as novel non-viral gene delivery nano-device. Cationic PLA-PEG nanoparticles were prepared by nanoprecipitation method. The gene loaded nanopartic...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Zou Weiwei, Liu Chunxi, Chen Zhijin, Zhang Na
Format: Artigo
Sprache:Inglês
Veröffentlicht: SpringerOpen 2009-01-01
Schriftenreihe:Nanoscale Research Letters
Schlagworte:
Cationic PLA-PEG nanoparticles (DNA-PLA-PEG-NPs)
Gene therapy
Nanoprecipitation method
Non-viral gene vector
Online-Zugang:http://dx.doi.org/10.1007/s11671-009-9345-3
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