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Formulation and Characterization of Epalrestat-Loaded Polysorbate 60 Cationic Niosomes for Ocular Delivery

The aim of this work was to develop niosomes for the ocular delivery of epalrestat, a drug that inhibits the polyol pathway and protects diabetic eyes from damage linked to sorbitol production and accumulation. Cationic niosomes were made using polysorbate 60, cholesterol, and 1,2-di-O-octadecenyl-3...

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Hauptverfasser: Axel Kattar, Ana Quelle-Regaldie, Laura Sánchez, Angel Concheiro, Carmen Alvarez-Lorenzo
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2023-04-01
Schriftenreihe:Pharmaceutics
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Online-Zugang:https://www.mdpi.com/1999-4923/15/4/1247
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