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An Ebox element in the proximal Gata4 promoter is required for Gata4 expression in vivo.

GATA4 is an essential transcription factor required for the development and function of multiple tissues, including a major role in gonadogenesis. Despite its crucial role, the molecular mechanisms that regulate Gata4 expression in vivo remain poorly understood. We recently found that the Gata4 gene...

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Autors principals: Alain Boulende Sab, Marie-France Bouchard, Mélanie Béland, Bruno Prud'homme, Ouliana Souchkova, Robert S Viger, Nicolas Pilon
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2011-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC3236771?pdf=render
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