Sphingosine Kinase 1 Aggravates Liver Fibrosis by Mediating Macrophage Recruitment and PolarizationSummary

Background & Aims: Sphingosine kinase 1 (SphK1) has distinct roles in the activation of Kupffer cells and hepatic stellate cells in liver fibrosis. Here, we aim to investigate the roles of SphK1 on hepatic macrophage recruitment and polarization in liver fibrosis. Methods: Liver fibrosis was ind...

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Detalhes bibliográficos

Principais autores:	Xin Ding, Xiang Zhang, Jiafan Cao, Shiyun Chen, Yinghua Chen, Kai Yuan, Bo Chen, Guizhi Yang, Shengwen Li, Jundong Yang, Guixiang Wang, Frank Tacke, Tian Lan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-01-01
Colecção:	Cellular and Molecular Gastroenterology and Hepatology
Assuntos:	Liver Fibrosis Macrophage Polarization Macrophage Recruitment SphK1
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2352345X24001619
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