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Stereospecific lactylation in bacteriology: L/D-lactate partitioning shapes host metabolic-disease axis

Two stereoisomers of lactate, L- and D-lactate, serve as critical conduits for bidirectional communication in host-bacteria interactions and the development of diseases. Lactylation, a novel post-translational modification (PTM), has been linked to the regulation of gene expression, immune responses...

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Autors principals: Sirui Wang, Leiliang Zhang
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2025-10-01
Col·lecció:Frontiers in Microbiology
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1693700/full
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