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Blockade of neutrophil recruitment to tumor sites based on sialic acid-modified nanoplatforms enhances the efficacy of checkpoint blockade immunotherapy

Checkpoint inhibitors are designed to rejuvenate depleted or suppressed T cells in the tumor microenvironment, relying on the immune system to control and kill tumors. However, accumulating evidence indicates that tumor-infiltrating neutrophils impede the proliferation and activation of T cells and...

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Detalhes bibliográficos
Principais autores: Meng Chen, Zhaowei Qi, Xianmin Meng, Shuo Wang, Xueying Zheng, Miao Hu, Xinrong Liu, Yanzhi Song, Yihui Deng
Formato: Artigo
Idioma:Inglês
Publicado em: KeAi Communications Co., Ltd. 2023-03-01
coleção:Asian Journal of Pharmaceutical Sciences
Assuntos:
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S1818087623000119
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