Heterocyclic sterol probes for live monitoring of sterol trafficking and lysosomal storage disorders

Abstract The monitoring of intracellular cholesterol homeostasis and trafficking is of great importance because their imbalance leads to many pathologies. Reliable tools for cholesterol detection are in demand. This study presents the design and synthesis of fluorescent probes for cholesterol recogn...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Jarmila Králová, Michal Jurášek, Lucie Krčová, Bohumil Dolenský, Ivan Novotný, Michal Dušek, Zdeňka Rottnerová, Michal Kahle, Pavel Drašar, Petr Bartůněk, Vladimír Král
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2018-09-01
Serie:	Scientific Reports
Soggetti:	Filipin Cholesterol Trafficking NPC Fibroblasts Dehydroergosterol (DHE) Abiraterone Acetate
Accesso online:	https://doi.org/10.1038/s41598-018-32776-6
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!