Apolipoprotein E-Mimetic Peptide COG1410 Promotes Autophagy by Phosphorylating GSK-3β in Early Brain Injury Following Experimental Subarachnoid Hemorrhage

COG1410, a mimetic peptide derived from the apolipoprotein E (apoE) receptor binding region, exerts positive effect on neurological deficits in early brain injury (EBI) after experimental subarachnoid hemorrhage (SAH). Currently the neuroprotective effect of COG1410 includes inhibiting BBB disruptio...

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Principais autores:	Xinshen Li, Jianhua Peng, Jinwei Pang, Yue Wu, Xueping Huang, Yong Li, Jian Zhou, Long Gu, Xiaochuan Sun, Ligang Chen, Michael P. Vitek, Yong Jiang
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2018-03-01
Serija:	Frontiers in Neuroscience
Teme:	subarachnoid hemorrhage early brain injury autophagy apolipoprotein E glycogen synthase kinase 3 beta
Online dostop:	http://journal.frontiersin.org/article/10.3389/fnins.2018.00127/full
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