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Apolipoprotein E-Mimetic Peptide COG1410 Enhances Retinal Ganglion Cell Survival by Attenuating Inflammation and Apoptosis Following TONI

Vision loss after traumatic optic nerve injury (TONI) is considered irreversible because of the retrograde loss of retinal ganglion cells (RGCs), which undergo inflammation and apoptosis. Previous studies have shown that COG1410, a mimic peptide derived from the apolipoprotein E (apoE) receptor bind...

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Principais autores: Li Kuai, Jianhua Peng, Yong Jiang, Zheng Zheng, Xiyuan Zhou
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Neuroscience
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Acceso en liña:https://www.frontiersin.org/article/10.3389/fnins.2019.00980/full
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