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Gene expression changes in cerebellum induced by dietary restriction

BackgroundDietary restriction (DR) is a well-established universal anti-aging intervention, and is neuroprotective in multiple models of nervous system disease, including models with cerebellar pathology. The beneficial effects of DR are associated with a rearrangement of gene expression that modula...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Lisanne J. van’t Sant, María B. Birkisdóttir, Rutger A. Ozinga, Ákos Gyenis, Jan H.J. Hoeijmakers, Wilbert P. Vermeij, Dick Jaarsma
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2023-05-01
Schriftenreihe:Frontiers in Molecular Neuroscience
Schlagworte:
Purkinje neurons
aging
neurodegeneration
neuroprotective mechanisms
neuronal signaling
DNA repair
Online-Zugang:https://www.frontiersin.org/articles/10.3389/fnmol.2023.1185665/full
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