Underestimated effect sizes in GWAS: fundamental limitations of single SNP analysis for dichotomous phenotypes.
Complex diseases are often highly heritable. However, for many complex traits only a small proportion of the heritability can be explained by observed genetic variants in traditional genome-wide association (GWA) studies. Moreover, for some of those traits few significant SNPs have been identified....
-д хадгалсан:
| Үндсэн зохиолчид: | , , , |
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| Формат: | Artigo |
| Хэл сонгох: | Inglês |
| Хэвлэсэн: |
Public Library of Science (PLoS)
2011-01-01
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| Цуврал: | PLoS ONE |
| Онлайн хандалт: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22140493/?tool=EBI |
| Шошгууд: |
Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!
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