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Nanobody-drug conjugates for targeting specific GPCR pairs.

Bitopic ligands that engage two distinct binding sites offer exciting opportunities for finely tuned control of G protein-coupled receptor signaling. A recent study in PLOS Biology employed click chemistry to generate novel nanobody-small molecule conjugates and demonstrated their logic-gated activi...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Xianglin Huang, Bryan L Roth
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Public Library of Science (PLoS) 2025-11-01
Rangatū:PLoS Biology
Urunga tuihono:https://doi.org/10.1371/journal.pbio.3003483
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