Metabolic engineering of Escherichia coli for optimized biosynthesis of nicotinamide mononucleotide, a noncanonical redox cofactor

Abstract Background Noncanonical redox cofactors are emerging as important tools in cell-free biosynthesis to increase the economic viability, to enable exquisite control, and to expand the range of chemistries accessible. However, these noncanonical redox cofactors need to be biologically synthesiz...

Полное описание

Библиографические подробности

Главные авторы:	William B. Black, Derek Aspacio, Danielle Bever, Edward King, Linyue Zhang, Han Li
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2020-07-01
Серии:	Microbial Cell Factories
Предметы:	Nicotinamide mononucleotide Noncanonical redox cofactor Escherichia coli Metabolic engineering NAD+ biosynthesis Biomimetic cofactor
Online-ссылка:	http://link.springer.com/article/10.1186/s12934-020-01415-z
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