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Onset of Telomere Dysfunction and Fusions in Human Ovarian Carcinoma

Telomere dysfunction has been strongly implicated in the initiation of genomic instability and is suspected to be an early event in the carcinogenesis of human solid tumors. Recent findings have established the presence of telomere fusions in human breast and prostate malignancies; however, the onse...

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Main Authors: Nazmul Huda, Yan Xu, Alison M. Bates, Deborah A. Rankin, Nagarajan Kannan, David Gilley
Format: Artigo
Language:Inglês
Published: MDPI AG 2019-05-01
Series:Cells
Subjects:
telomere
telomere dysfunction
ovarian carcinoma
telomerase
genomic instability
Online Access:https://www.mdpi.com/2073-4409/8/5/414
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