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Binding of alpha-ACTN4 to EGF receptor enables its rapid phosphorylation

Alpha-ACTN4, a member of alpha-actinin family is critical for cell motility through its regulated binding of actin filaments. We previously found that EGF exposure of cells triggers the tyrosyl-phosphorylation of ACTN4 in fibroblasts that dramatically downregulates its binding to actin filaments. Ho...

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Autori principali: Hanshuang Shao, Alan Wells
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2021-01-01
Serie:Heliyon
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Accesso online:http://www.sciencedirect.com/science/article/pii/S240584402100116X
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