JTT-553, a novel Acyl CoA:diacylglycerol acyltransferase (DGAT) 1 inhibitor, improves glucose metabolism in diet-induced obesity and genetic T2DM mice
Type 2 diabetes mellitus (T2DM) arises primarily due to lifestyle factors and genetics. A number of lifestyle factors are known to be important in the development of T2DM, including obesity. JTT-553, a novel Acyl CoA:diacylglycerol acyltransferase 1 inhibitor, reduced body weight depending on dietar...
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| Principais autores: | , , , , , , , |
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| 格式: | Artigo |
| 语言: | Inglês |
| 出版: |
Elsevier
2015-09-01
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| 丛编: | Journal of Pharmacological Sciences |
| 主题: | |
| 在线阅读: | http://www.sciencedirect.com/science/article/pii/S1347861315001802 |
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