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The role of HECT-type E3 ubiquitin ligases in inflammation

Homologous to the E6-AP Carboxyl Terminus (HECT)-type E3 ubiquitin ligases are key components of the ubiquitin-proteasome system (UPS) and play an important role in the regulation of inflammatory responses. Inflammation serves as a core defense mechanism of the host against infection and tissue dama...

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Hoofdauteurs: Ziyi Wang, Peirui Wang, Huawang Xie, Zhibo You, Xiping Liu, Fang Cao, Shengtao Yao
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2026-04-01
Reeks:Frontiers in Immunology
Onderwerpen:
HECT-type E3 ubiquitin ligases
HERC subfamily
inflammation
NEDD4subfamily
other HECTs
signaling pathways
Online toegang:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1810360/full
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