IL-6 promotes tumor growth through immune evasion but is dispensable for cachexia
Abstract Various cytokines have been implicated in cancer cachexia. One such cytokine is IL-6, deemed as a key cachectic factor in mice inoculated with colon carcinoma 26 (C26) cells, a widely used cancer cachexia model. Here we tested the causal role of IL-6 in cancer cachexia by knocking out the I...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Springer Nature
2024-04-01
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| Серии: | EMBO Reports |
| Предметы: | |
| Online-ссылка: | https://doi.org/10.1038/s44319-024-00144-3 |
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