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IL-6 promotes tumor growth through immune evasion but is dispensable for cachexia

Abstract Various cytokines have been implicated in cancer cachexia. One such cytokine is IL-6, deemed as a key cachectic factor in mice inoculated with colon carcinoma 26 (C26) cells, a widely used cancer cachexia model. Here we tested the causal role of IL-6 in cancer cachexia by knocking out the I...

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Bibliografiset tiedot
Päätekijät: Young-Yon Kwon, Sheng Hui
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer Nature 2024-04-01
Sarja:EMBO Reports
Aiheet:
Linkit:https://doi.org/10.1038/s44319-024-00144-3
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