Peptide Drug Release Behavior from Biodegradable Temperature-Responsive Injectable Hydrogels Exhibiting Irreversible Gelation

We investigated the release behavior of glucagon-like peptide-1 (GLP-1) from a biodegradable injectable polymer (IP) hydrogel. This hydrogel shows temperature-responsive irreversible gelation due to the covalent bond formation through a thiol-ene reaction. In vitro sustained release of GLP-1 from an...

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Autors principals:	Kazuyuki Takata, Hiroki Takai, Yuta Yoshizaki, Takuya Nagata, Keisuke Kawahara, Yasuyuki Yoshida, Akinori Kuzuya, Yuichi Ohya
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2017-10-01
Col·lecció:	Gels
Matèries:	injectable polymers sustained release sol-to-gel transition hydrogel peptide drug delivery
Accés en línia:	https://www.mdpi.com/2310-2861/3/4/38
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