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Peptide Drug Release Behavior from Biodegradable Temperature-Responsive Injectable Hydrogels Exhibiting Irreversible Gelation

We investigated the release behavior of glucagon-like peptide-1 (GLP-1) from a biodegradable injectable polymer (IP) hydrogel. This hydrogel shows temperature-responsive irreversible gelation due to the covalent bond formation through a thiol-ene reaction. In vitro sustained release of GLP-1 from an...

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Asıl Yazarlar: Kazuyuki Takata, Hiroki Takai, Yuta Yoshizaki, Takuya Nagata, Keisuke Kawahara, Yasuyuki Yoshida, Akinori Kuzuya, Yuichi Ohya
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI AG 2017-10-01
Seri Bilgileri:Gels
Konular:
injectable polymers
sustained release
sol-to-gel transition
hydrogel
peptide drug delivery
Online Erişim:https://www.mdpi.com/2310-2861/3/4/38
Etiketler: Etiketle
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