Identification of predictors of drug sensitivity using patient-derived models of esophageal squamous cell carcinoma

Predicting the drug response of patients with cancer is crucial for implementing targeted therapy. Here, Su et al. make patient-derived cell lines and perform targeted sequencing and RNA-seq to identify CDKN2A/2B loss as a predictor of response to CDK4/6 inhibitors in esophageal squamous cell carcin...

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Detalhes bibliográficos

Principais autores:	Dan Su, Dadong Zhang, Jiaoyue Jin, Lisha Ying, Miao Han, Kaiyan Chen, Bin Li, Junzhou Wu, Zhenghua Xie, Fanrong Zhang, Yihui Lin, Guoping Cheng, Jing-Yu Li, Minran Huang, Jinchao Wang, Kailai Wang, Jianjun Zhang, Fugen Li, Lei Xiong, Andrew Futreal, Weimin Mao
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2019-11-01
coleção:	Nature Communications
Acesso em linha:	https://doi.org/10.1038/s41467-019-12846-7
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