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A cyclin-dependent kinase inhibitor, dinaciclib in preclinical treatment models of thyroid cancer.

We explored the therapeutic effects of dinaciclib, a cyclin-dependent kinase (CDK) inhibitor, in the treatment of thyroid cancer.Seven cell lines originating from three pathologic types of thyroid cancer (papillary, follicular and anaplastic) were studied. The cytotoxicity of dinaciclib was measured...

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Príomhchruthaitheoirí: Shu-Fu Lin, Jen-Der Lin, Chuen Hsueh, Ting-Chao Chou, Richard J Wong
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Public Library of Science (PLoS) 2017-01-01
Sraith:PLoS ONE
Rochtain ar líne:http://europepmc.org/articles/PMC5312924?pdf=render
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