Deletion of Cytoplasmic Double-Stranded RNA Sensors Does Not Uncover Viral Small Interfering RNA Production in Human Cells

ABSTRACT Antiviral immunity in insects and plants is mediated by the RNA interference (RNAi) pathway in which viral long double-stranded RNA (dsRNA) is processed into small interfering RNAs (siRNAs) by Dicer enzymes. Although this pathway is evolutionarily conserved, its involvement in antiviral def...

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Detalles Bibliográficos

Principais autores:	Susan Schuster, Lotte E. Tholen, Gijs J. Overheul, Frank J. M. van Kuppeveld, Ronald P. van Rij
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology 2017-08-01
Series:	mSphere
Assuntos:	RNA interference RNA virus innate immunity
Acceso en liña:	https://journals.asm.org/doi/10.1128/mSphere.00333-17
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