Development and Validation of Rapid RP-HPLC and Green Second-Derivative UV Spectroscopic Methods for Simultaneous Quantification of Metformin and Remogliflozin in Formulation Using Experimental Design

Recently, a new formulation containing metformin HCl (MFH) and remogliflozin etabonate (RGE) has been approved for the management of diabetes mellitus. However, only one analytical method has been reported for the simultaneous determination of both the analytes. Therefore, the current study was desi...

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Autori principali:	Mahesh Attimarad, Rafea Elamin Elgack Elgorashe, Rajasekaran Subramaniam, Mohammed Monirul Islam, Katharigatta N. Venugopala, Sreeharsha Nagaraja, Abdulmalek Ahmed Balgoname
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2020-10-01
Serie:	Separations
Soggetti:	metformin remogliflozin HPLC box–behnken design derivative spectroscopy optimization
Accesso online:	https://www.mdpi.com/2297-8739/7/4/59
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