Development and Validation of Rapid RP-HPLC and Green Second-Derivative UV Spectroscopic Methods for Simultaneous Quantification of Metformin and Remogliflozin in Formulation Using Experimental Design

Recently, a new formulation containing metformin HCl (MFH) and remogliflozin etabonate (RGE) has been approved for the management of diabetes mellitus. However, only one analytical method has been reported for the simultaneous determination of both the analytes. Therefore, the current study was desi...

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Автори:	Mahesh Attimarad, Rafea Elamin Elgack Elgorashe, Rajasekaran Subramaniam, Mohammed Monirul Islam, Katharigatta N. Venugopala, Sreeharsha Nagaraja, Abdulmalek Ahmed Balgoname
Формат:	Artigo
Мова:	Inglês
Опубліковано:	MDPI AG 2020-10-01
Серія:	Separations
Предмети:	metformin remogliflozin HPLC box–behnken design derivative spectroscopy optimization
Онлайн доступ:	https://www.mdpi.com/2297-8739/7/4/59
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