An early, reversible cholesterolgenic etiology of diet-induced insulin resistance

Objective: A buildup of skeletal muscle plasma membrane (PM) cholesterol content in mice occurs within 1 week of a Western-style high-fat diet and causes insulin resistance. The mechanism driving this cholesterol accumulation and insulin resistance is not known. Promising cell data implicate that th...

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Manylion Llyfryddiaeth

Prif Awduron:	Jacob D. Covert, Brian A. Grice, Matthew G. Thornburg, Manpreet Kaur, Andrew P. Ryan, Lixuan Tackett, Theja Bhamidipati, Natalie D. Stull, Teayoun Kim, Kirk M. Habegger, Donald A. McClain, Joseph T. Brozinick, Jeffrey S. Elmendorf
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Elsevier 2023-06-01
Cyfres:	Molecular Metabolism
Pynciau:	Cholesterol Insulin resistance Membrane Skeletal muscle
Mynediad Ar-lein:	http://www.sciencedirect.com/science/article/pii/S2212877823000492
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!